Raise blood pressure
Cause fluid retention
Affect kidney function
Interfere with certain blood-pressure medicines

Older adults who use NSAIDs frequently should discuss the safest dose and duration with their healthcare professional.

2. Some Decongestants

Cold and allergy medications sometimes contain stimulants designed to shrink swollen blood vessels inside the nose.

Common examples include products containing:

Pseudoephedrine
Phenylephrine

Because these medicines constrict blood vessels, they may temporarily raise blood pressure and heart rate.

This may be more important for people with:

Uncontrolled hypertension
Coronary artery disease
Previous stroke
Certain heart rhythm disorders

A person with cardiovascular disease should check with a pharmacist or doctor before routinely using oral decongestants.

3. Some Hormone Treatments

Certain hormone-containing medications can affect the risk of blood clot formation.

Depending on the formulation and individual risk factors, estrogen-containing therapies may increase the likelihood of venous blood clots and, in selected people, stroke or other cardiovascular complications.

Risk is influenced by factors such as: